2024

Molecular mechanism of parental H3/H4 recycling at a replication fork

F Nagae , Y Murayama , T Terakawa
Nature Communications 15 : 9485

2023

Histone chaperone Nap1 dismantles an H2A/H2B dimer from a partially unwrapped nucleosome

F Nagae , S Takada , T Terakawa
Nucleic Acids Research 51 : 5351

2022

ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures

N Sekiyama , K Takaba , S Maki-Yonekura , KI Akagi , Y Ohtani , K Imamura , T Terakawa , K Yamashita , D Inaoka , K Yonekura , TS Kodama , H Tochio
Proceedings of the National Academy of Sciences 119 : e2122523119

Coarse-grained molecular dynamics simulations of base-pair mismatch recognition protein MutS sliding along DNA

K Inoue , S Takada , T Terakawa
Biophysics and Physicobiology 19 : e190015

2021

Single-molecule junction spontaneously restored by DNA zipper

T Harashima , S Fujii , Y Jono , T Terakawa , N Kurita , S Kaneko , M Kiguchi , T Nishino
Nature Communications 12 : 5762

The lane-switch mechanism for nucleosome repositioning by DNA translocase

F Nagae , GB Brandani , S Takada , T Terakawa
Nucleic acids research 49 : 9066

Modeling of DNA binding to the condensin hinge domain using molecular dynamics simulations guided by atomic force microscopy

H Koide , N Kodera , S Bisht , S Takada , T Terakawa
PLoS computational biology 17 : e1009265

2019

Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination

JB Steinfeld , O Belan , Y Kwon , T Terakawa , A Al-Zain , MJ Smith , JB Crickard , Z Qi , W Zhao , R Rothstein , LS Symington , P Sung , SJ Boulton , EC Greene
Genes & Development 33 : 1191

Nucleosome Crowding in Chromatin Slows the Diffusion but Can Promote Target Search of Proteins

R Kanada , T Terakawa , H Kenzaki , S Takada
Biophysical journal 116 : 2285

2017

The condensin complex is a mechanochemical motor that translocates along DNA

T Terakawa , S Bisht , JM Eeftens , C Dekker , CH Haering , EC Greene
Science 358 : 672

Sequential eviction of crowded nucleoprotein complexes by the exonuclease RecBCD molecular motor

T Terakawa , S Redding , TD Silverstein , EC Greene
Proceedings of the National Academy of Sciences 114 : E6322

How one-dimensional diffusion of transcription factors are affected by obstacles: coarse-grained molecular dynamics study

M Saito , T Terakawa , S Takada
Molecular Simulation 43 : 1315

2016

Dynamic coupling among protein binding, sliding, and DNA bending revealed by molecular dynamics

C Tan , T Terakawa , S Takada
Journal of the American Chemical Society 138 : 8512

2015

p53 dynamics upon response element recognition explored by molecular simulations

T Terakawa , S Takada
Scientific reports 5 : 17107

Modeling Structural Dynamics of Biomolecular Complexes by Coarse-Grained Molecular Simulations

S Takada , R Kanada , C Tan , T Terakawa , W Li , H Kenzaki
Accounts of Chemical Research 48 : 3026

DNA RECOMBINATION. Base triplet stepping by the Rad51/RecA family of recombinases

JY Lee , T Terakawa , Z Qi , JB Steinfeld , S Redding , Y Kwon , WA Gaines , W Zhao , P Sung , EC Greene
Science 349 : 977

2014

Multi-scale ensemble modeling of modular proteins with intrinsically disordered linker regions: application to p53

T Terakawa , J Higo , S Takada
Biophysical journal 107 : 721

RESPAC: Method to Determine Partial Charges in Coarse-Grained Protein Model and Its Application to DNA-Binding Proteins

T Terakawa , S Takada
Journal of Chemical Theory and Computation 10 : 711

2012

p53 searches on DNA by rotation-uncoupled sliding at C-terminal tails and restricted hopping of core domains

T Terakawa , H Kenzaki , S Takada
Journal of the American Chemical Society 134 : 14555

Energy landscape and multiroute folding of topologically complex proteins adenylate kinase and 2ouf-knot

W Li , T Terakawa , W Wang , S Takada
Proceedings of the National Academy of Sciences 109 : 17789

2011

Multiscale ensemble modeling of intrinsically disordered proteins: p53 N-terminal domain

T Terakawa , S Takada
Biophysical journal 101 : 1450

2010

On easy implementation of a variant of the replica exchange with solute tempering in GROMACS

T Terakawa , T Kameda , S Takada
Journal of computational chemistry 32 : 1228